Specific Objectives of MyoNet
⇛ To implement the use of a myositis register (EuroMyositis) centred on a novel, electronic, web-based format to facilitate longitudinal collection of clinical and laboratory data in a standardised form using outcome measures that have been validated and are recommended by international myositis expertise within the International Myositis Assessment and Clinical Studies (IMACS).
⇛ To develop patient-administrated electronic forms to facilitate data collection in the EuroMyositis database.
⇛ To implement the use of this electronic system in clinical practice amongst myositis research centres.
⇛ To collect longitudinal clinical data from at least 1350 European patients with myositis.
⇛ To create a database with genetic data from a genome-wide association analysis (GWAS) and serology data from at least 1350 European patients with myositis and to link this to the clinical database.
⇛ To define autoantibody profiles concerning myositis-specific and myositis-associated autoantibodies and to identify new autoantibodies.
⇛ To identify diagnostic/prognostic biomarkers from the database and the register by integrating and analysing the clinical data with genetic and serology data.
⇛ To use the network and myositis register to facilitate new clinical trials.
⇛ To create a platform for functional cellular and molecular studies.
⇛ To facilitate training of young clinician scientists within this research field.